Table of Contents:

        Anatomy and Physiology of the Gene
        Epigenetics and Epigenomics
        Genomic Approaches to Hematology
        Regulation of Gene Expression, Transcription, Splicing and RNA Metabolism
        Protein Synthesis, Processing, and Trafficking
        Protein Architecture: Relationship of Form and Function
        Signaling Transduction and Metabolomics
        Pharmacogenomics and Hematologic Diseases
        Hematopoietic Stem Cell Biology
        Stem Cell Model of Hematologic Malignancies
        Hematopoietic Microenvironment
        Cell Adhesion
        Hematopoietic Cell Trafficking and Chemokines
        Interactions between Hematopoietic Stem and Progenitor Cells and the Bone Marrow: Current Biology of Stem Cell Homing and Mobilization
        Vascular Growth in Health and Disease
        Cytokine/Receptor families and signal transduction
        Control of Cell Division
        Cell Death
        Overview and Compartmentalization of the Immune System
        B-Cell Development
        T-Cell Immunity
        Natural Killer Cell Immunity
        Dendritic Cell Biology
        Complement and Immunoglobulin biology leading to clinical translation
        Tolerance and Autoimmunity
        Biology of Erythropoiesis, Erythroid Differentiation, and Maturation
        Granulocytopiesis and Monocytopoiesis
        Thrombocytopoiesis
        Inherited Forms of Bone Marrow Failure
        Aplastic Anemia
        Paroxysmal Nocturnal Hemoglobinuria
        Acquired Disorders of Unilineage Blood Cell Production
        Pathobiology of the Human Erythrocyte and Its Hemoglobins
        Approach to Anemia in the Adult and Child
        Pathophysiology of Iron Homeostasis
        Disorders of Iron Metabolism: Iron Deficiency and Overload
        Anemia of Chronic Diseases
        Heme Biosynthesis and Its Disorders: Porphyrias and Sideroblastic Anemias
        Megaloblastic Anemias
        Thalassemia Syndromes
        Pathobiology of Sickle Cell Disease
        Sickle Cell Disease: Clinical Features and Management
        Hemoglobin Variants Associated with Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias
        Red Blood Cell Enzymopathies
        Red Blood Cell Membrane Disorders
        Autoimmune Hemolytic Anemia
        Extrinsic Nonimmune Hemolytic Anemias
        Granulocytosis, Granulocytopenia, Monocytosis, and Monocytopenia
        Lymphocytosis, Lymphocytopenia, Hypergammaglobulinemia, and Hypogammaglobulinemia
        Disorders of Phagocyte Function
        Congenital Disorders of Lymphocyte Function
        Histiocytic Disorders
        Lysosomal Storage Diseases: Perspectives and Principles
        Infectious Mononucleosis and Other Epstein-Barr Virus-Associated Diseases
        Progress in the Classification of Hematopoietic and Lymphoid Neoplasms: Clinical Implications
        The CytoGenomic Basis of Hematological Malignancies
        Pharmacology and Molecular Mechanisms of Antineoplastic Agents for Hematologic Malignancies
        Pathobiology of Acute Myeloid Leukemia
        Clinical Manifestations and Treatment of Acute Myeloid Leukemia
        Myelodysplastic Syndromes: Biology and Treatment
        Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome in Adults
        Acute Myeloid Leukemia in Children
        Myelodysplastic Syndrome and Myeloproliferative Syndrome in Children
        Pathobiology of Acute Lymphoblastic Leukemia
        Clinical Manifestations and Treatment in Children of Acute Lymphoblastic Leukemia
        Acute Lymphocytic Leukemia in Adults
        Chronic Myeloid Leukemia
        The Polycythemias
        Essential Thrombocythemia
        Primary Myelofibrosis
        Eosinophilia, Eosinophil-Associated Diseases, Chronic Eosinophil Leukemia, and the Hypereosinophilic Syndromes
        Mast Cells and Systemic Mastocytosis
        The Pathologic Basis for the Classification of Non-Hodgkin and Hodgkin Lymphomas
        Origins of Hodgkin Disease
        Hodgkin Lymphoma: Clinical Manifestations, Staging, and Therapy
        Origins of Non-Hodgkin Lymphomas
        Chronic Lymphocytic Leukemia
        Hairy Cell Leukemia
        Clinical Manifestations and Treatment of Indolent Lymphomas: Marginal Zone Lymphomas (Extranodal/Malt, Splenic, and Nodal)
        Clinical Manifestations, Staging, and Treatment of Follicular Lymphoma
        Mantle Cell Lymphoma
        Diagnosis and Treatment of Diffuse Large B-Cell Lymphoma (DLBCL) and Burkitt Lymphoma (BL)
        Viral-Related Lymphomas
        Malignant Lymphomas in Childhood
        T-Cell Lymphomas
        Multiple Myeloma
        Waldenstrom Macroglobulinemia/Lymphoplasmacytic Lymphoma
        Immunoglobuin Light-Chain Amyloidosis (Primary Amyloidosis)
        Clinical Approach to Infections in the Compromised Host
        Psychosocial Aspects of Hematologic Disorders
        Pain Management and Antiemetic Therapy in Hematologic Disorders
        Palliative Care
        Late Complications of Hematologic Diseases and Their Therapies
        Overview and Historical Perspective of Current Cell-Based Therapies
        Practical Aspects of Hematologic Stem Cell Harvesting and Mobilization
        IND Enabling Processes for Cell-Based Therapies
        Graft Engineering and Cell Processing
        Principles of Cell-Based Genetic Therapies
        Mesenchymal Stromal Cells
        T Cell Therapy of Hematological Diseases
        NK Cell-Based Therapies
        Immune Checkpoint Blockade in Hematologic Malignancies
        Overview and Choice of Donor of Hematopoietic Stem Cell Transplantation
        Indications and Outcomes of Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies in Adults
        Unrelated Donor Hematopoietic Cell Transplantation
        Haploidentical Hematopoietic Cell Transplantation
        Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies
        Graft-versus-Host Disease and Graft-versus-Leukemia Responses: Biology and Therapy
        Complications after Hematopoietic Cell Transplantation
        Human Blood Group Antigens and Antibodies
        Principles of Red Blood Cell Transfusion
        Clinical Considerations in Platelet Transfusion Therapy
        Human Leukocyte Antigen and Human Neutrophil Antigen Systems
        Principles of Neutrophil (Granulocyte) Transfusions
        Transfusion of Plasma Derivatives: Plasma, Cryoprecipitate, Albumin, and Immunoglobulins
        Preparation of Plasma-Derived and Recombinant Human Plasma Proteins
        Transfusion Therapy for Coagulation Factor Deficiencies
        Hemapheresis
        Transfusion Reactions to Blood and Cell Therapy Products
        Transfusion-Transmitted Diseases
        Pediatric Transfusion Medicine
        Overview of Hemostasis and Thrombosis
        The Blood Vessel Wall
        Megakaryocyte and Platelet Structure
        Molecular Basis of Platelet Function
        Molecular Basis of Blood Coagulation
        Regulatory Mechanisms in Hemostasis
        Clinical Approach to the Patient with Bleeding or Bruising
        Laboratory Evaluation of Hemostatic and Thrombotic Disorders
        Acquired Disorders of Platelet Function
        Diseases of Platelet Number: Immune Thrombocytopenia, Neonatal Alloimmune Thrombocytopenia, and Posttransfusion Purpura
        Thrombocytopenia Caused by Platelet Destruction, Hypersplenism, or Hemodilution
        Heparin-Induced Thrombocytopenia
        Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic Syndromes
        Hemophilia A and B
        Inhibitors in Hemophilia A and B
        Rare Coagulation Factor Deficiencies
        Structure, Biology, and Genetics of Von Willebrand Factor
        Disseminated Intravascular Coagulation
        Hypercoagulable States
        The Antiphospholipid Syndrome
        Venous Thromboembolism
        Mechanical Interventions in Arterial and Venous Thrombosis
        Atherothrombosis
        Stroke
        Acute Coronary Syndromes
        Atrial Fibrillation
        Peripheral Artery Disease
        Antithrombotic Drugs
        Disorders of Coagulation in the Neonate
        Hematologic Changes of Pregnancy
        Hematologic Manifestations of Childhood Illness
        Hematologic Manifestations of Systemic Disease: Liver Disease
        Hematologic Manifestations of Systemic Disease: Renal Disease
        Hematologic Manifestations of Cancer
        Integrated Therapies in Patients with Hematologic Diseases
        Hematologic Manifestations of AIDS
        Hematologic Manifestations of Parasitic Diseases
        Hematologic Problems in the Surgical Patient: Bleeding and Thrombosis
        The Spleen and Its Disorders
    Hematology in Aging
APPENDIX:
Resources for the Hematologist: Interpretive Comments and Selected Reference Values for Neonatal, Pediatric, and Adult Populations