New To This Edition:
Features a brand new, full-color design with hundreds of new figures, tables, algorithms, and micrographs.
Includes two entirely new chapters: Neurodevelopmental Follow-Up and Stroke in the Newborn; a new section on Neonatal Seizures; and an extensively expanded section on Hypoxic-Ischemia and Other Disorders.
Showcases the experience and knowledge of a new editorial team, led by Dr. Joseph Volpe and Dr. Terrie E. Inder, Chair of the Department of Pediatric Newborn Medicine at Brigham and Women’s Hospital, all of whom bring a wealth of insight to this classic text.
Offers comprehensive updates from cover to cover to reflect all of the latest information regarding the development of the neural tube; prosencephalic development; congenital hydrocephalus; cerebellar hemorrhage; neuromuscular disorders and genetic testing; and much more.
Uses an improved organization to enhance navigation.
Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.
Table Of Contents:
Unit I: Human Brain Development
Overview
1. Neural Tube Development and Defects
2. Prosencephalic Development and Defects
3. Congenital Hydrocephalus
4. Cerebellar Development and Defects
5. Neuronal Proliferative Events and Defects
6. Neuronal Migrational Events and Defects
7. Organizational Events and Defects
8. Myelination Events and Defects
Unit II: Neurological Evaluation
Overview
9. Neurological Examination: Normal and Abnormal Features
10. Specialized Neurological Studies
11. Neurodevelopmental Followup
Unit III: Neonatal Seizures
Overview
12. Neonatal Seizures
Unit IV: Hypoxic-ischemic and Related Disorders
Overview
13. Pathophysiology General Principles
14. Encephalopathy of the Preterm - Neuropathology
15. Encephalopathy of the Preterm - Pathophysiology
16. Encephalopathy of the Preterm - Clinical - Neurological Features, Diagnosis, Imaging, Prognosis, Therapy
17. Intrauterine, Intrapartum Assessments in the Term Infant
18. Hypoxic Ischemic Injury in the Term Infant - Neuropathology
19. Hypoxic Ischemic Injury in the Term Infant - Pathophysiology
20. Hypoxic Ischemic Injury in the Term Infant - Clinical - Neurological Features, Diagnosis, Imaging, Prognosis, Therapy
21. Stroke in the Newborn
Unit V: Intracranial Hemorrhage
Overview
22. Intracranial/Hemorrhage - Supratentorial (Subdural, Subarachnoid, Intraventricular (Term Infant), Miscellaneous
23. Intracranial Hemorrhage Infratentorial/Cerebellar
24. Preterm IVH/Posthemorrhagic Hydrocephalus
Unit VI: Metabolic Encephalopathies
Overview
25. Glucose
26. Bilirubin
27. Amino acids
28. Organic acids
Unit VII: Degenerative Disorders
29. Degenerative Disorders of the Newborn
Unit VIII: Neuromuscular Disorders
Overview
30. Evaluation, Specialized Studies
31. Arthrogryposis Multiplex Congenita
32. Levels Above Lower Motor Neuron to Neuromuscular Junction
33. Muscle Involvement and Restricted Disorders
Unit IX: Intracranial Infections
Overview
34. Viral, Protozoan and Related Intracranial Infections
35. Bacterial and Fungal Intracranial Infections
Unit X: Perinatal Trauma
36. Injuries of Extracranial, Cranial, Intracranial, Spinal Cord and Peripheral Nervous System Structures
Unit XI: Intracranial Mass Lesions
37. Brain Tumors and Vein of Galen Malformations
Unit XII: Drugs and the Developing Nervous System
Overview
38. Passive Addiction and Teratogenic Effects
